Yeah I had this problem too, so I just did myself a favour, turn it to trusted and also had to turn of smart screen on IE 11 as it was starting to flag a whole bunch of things I have used for years and not allow installs for some of the stuff that I have used for years and have downloaded to my system for years, etc. I notice that Windows 10 Pro seems to need like any real new OS from Microshaft, to be updated and tweaked to get it to run decently, essentially its like this on every new OS release it seems!
Cheers!
P.S. I will be going with Bitdefender when my Eset runs out, they are really the best in the last couple of years and they have a really small footprint too!