I am seeing this same error. In my case I have ripped the DVD to a Video_TS file and am using DVDFab 6.2.2.0 Beta to compress the file (6.51GB) and create an .ISO backup. This has worked successfully on several disks until Disney's Pirates of the Caribbean. This has become my evaluation movie before buying, and so far no other software has been able to handle it. DVDFab has done better, so I'm hopeful.
Internal log
VDFab 6.2.2.0 (2010/01/18 10:16:39)
0m 00.62s: option dvd2dvd 1 dvd2mobile 1 bluray2bluray 1 file2mobile 1 filemover 1
Process log:10:17:37: You are going to try "DVD to DVD" option.
10:17:37: Analyzing of DVD started
10:17:37: Analyzing of DVD completed successfully
10:17:37: Copy process started
10:17:37: Task_1 failed! Error=400()
Ripping either with MacTheRipper 2.6.6 or Ripit (1.3.3) gives the same result
DVDFab is loaded under wine on a MacBook Pro running OS X 10.5
The Beta version does actually populate the main window with available titles, trying to view the movie preview brings up the error report window
Internal log

0m 00.62s: option dvd2dvd 1 dvd2mobile 1 bluray2bluray 1 file2mobile 1 filemover 1
Process log:10:17:37: You are going to try "DVD to DVD" option.
10:17:37: Analyzing of DVD started
10:17:37: Analyzing of DVD completed successfully
10:17:37: Copy process started
10:17:37: Task_1 failed! Error=400()
Ripping either with MacTheRipper 2.6.6 or Ripit (1.3.3) gives the same result
DVDFab is loaded under wine on a MacBook Pro running OS X 10.5
The Beta version does actually populate the main window with available titles, trying to view the movie preview brings up the error report window
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